眼手术后干眼症的临床观察

Dry eye after ophthalmic surgery

目的探讨眼手术后干眼症的病因，诊断和治疗。方法对眼部手术后有干眼症状的132例（149只眼），就诊前所行手术，眼局部用药情况、治疗前后，停止治疗前后基础泪液分泌实验（Schirmertest）、泪膜破裂时间（BUT）实验和荧光苏染色的变化情况进行分析。根据病情停用原来的眼药水，辅以不含防腐剂的人工泪液（透明质酸钠）和促上皮生长的滴眼液（碱性成纤维细胞生长因子basic fibroblast growthfactor，bFGF）滴眼液。结果分别对治疗前、治疗后、有效者停止治疗一周后的基础泪液分泌、泪膜破裂时间（BUT）进行比较，差异显著有统计学意义（P〈0．01）。结论眼科手术易诱发干眼症，早期明确诊断，选择正确的治疗方法，可以取得较好的疗效。

Objective To discuss the etiology, diagnosis and treatment of dry eye after eye surgery. Methods there are 132 （ 149 eyes）examples of dry eye symptom in clinical service, every example recorded the surgery been operated and eye drop has used.prior and post treatment, prior and post stop treatment basic Schirmer test,BUT （tear-break-time）experiment,fluorescein staining and analysised the condition of change; All of the patients stopped using eye drops and give the artificial tears（sodium hyaluronate）not containing anti- septic and the medicine of ocular surface epithelium repairing （bFGF）.Results We compared the result of Schirmer test and BUT experiment between prior treatment and post treatment,prior and post stop treatment, found that the difference is significantly （P 〈0.01 ）.Conclusion the srugery on eye can induce dry eye;we should play an emphasis on it to diagnose earlier, and choose the proper treatment, the curative effect is significant.