膜片钳放大器自动测试方法的研究

Study on Automatic Test of Computer-controlled Patch-clamp Amplifier

为了准确、快速的检测膜片钳放大器的性能参数,判断其是否正常工作,研究与设计了一种自动测试方法。利用计算机和参数控制与数据采集器对膜片钳放大器进行数字控制和参数检测,并采用最小二乘拟合等算法计算相关参数。实验结果证明自动测试方法能在四到五分钟内测试出放大器各模块的性能参数,并在设备非正常工作时找出潜在的故障点。

In order to obtain the performance parameters and estimate the operation state of the patch-clamp amplifier quickly and accurately, a novel method of automatic test was developed. The routine controls and inspects the patch-clamp amplifier by employing the personal computer and data acquisition, and then evaluates the analog parameters using relative arithmetic. The experimental results demonstrated that all parameters of each functional circuit can be obtained by the routine within about 4-5 minutes, and the potential malfunctions can be find exactly when the amplifier works improperly.