X线钼靶摄影与超声诊断乳腺微钙化灶的对比研究

Comparative Study of Mammography with Ultrasonography for the Diagnosis of Breast disease with Microcalcification

目的:比较X线钼靶摄影与超声在乳腺微钙化灶诊断中的价值。方法:收集伴随微钙化灶(经X线钼靶摄影确诊)的乳腺良性、恶性疾病患者117例,分析超声对乳腺微钙化的检出率;比较X线钼靶摄影与超声检查对乳腺微钙化灶病例诊断的敏感性、特异性及准确性。结果:乳腺微钙化的超声检出率为66.7%,其中乳腺恶性病灶的微钙化超声检出率为87.5%,乳腺良性病变的微钙化灶超声检出率为33.3%,超声诊断乳腺微钙化灶病例的敏感性、特异性和准确性分别为69.4%、86.7%和76.1%,X线钼靶摄影分别为75.0%、73.3%、74.3%,两者联合应用为90.2%、91.1%、90.5%。结论:X线钼靶摄影与超声相比,前者具有较高的敏感性,后者具有较高的特异性,而两者联合应用可提高对乳腺微钙化灶病例诊断的准确率,对于乳腺癌的早期诊断具有较高的临床实用价值。

Objective：To explore the diagnostic value of mammography and ultrasonography（US）in diagnosis of breast disease with microcalcifications.Methods：Seventy-eight cases with breast microcalcifications were detected by mammography.The detection rate of breast microcalcification at US was analyzed.And the sensitivity,specificity and the accuracy of US in diagnosis breast disease with microcalcifications was compared with these of mammography.Results：The detection rate of breast microcalcification was 66.7%,And US depicted more malignant（87.5%）than benign microcalcification（33.3%）.The sensitivity specificity and accuracy of US was 68.7%、83.3%、 74.3%respectively,and the sensitivity specificity and accuracy of mammography was 72.9%、 73.3%、75.6%respectively,there were no significant difference between the two methods.The sensitivity,specificity and accuracy of the combined the two methods was 89.6%,90.0%,92.3% respectively.Conclusion：US can effectively detect and identify the breast microcalicications.The combination can improve the assessment of breast disease with microcalicications,and has a significant clinical practical value in diagnosis of early breast cancer.