附睾腺瘤样瘤5例组织学和免疫组化观察

A histologic and immunohistochemical study of 5 adenomatoid tumors in epididymis

本文对5例附睾腺瘤样瘤的组织学和免疫组化特征进行了观察。结果表明，肿瘤对细胞角蛋白（cytokeratin）、上皮膜抗原（EMA）和波形蛋白（vementin）均呈阳性反应，对第八因子相关抗原（FvlllRAg）均呈阴性表达。这些结果明确揭示了肿瘤细胞的双向分化特征，进一步支持该瘤间皮起源的观点。在病理诊断中，该瘤须与上皮样血管瘤和腺癌进行鉴别。

The observational results on histology and immunohistochemistry of 5 adenomatoid tumors in epididymis showed that there were strong positive expressions for cytokeratin, epithelial membrane antigen (EMA) and vementin, and negativity for factor Vlll-related antigen(FVlllRAg) in all tumor cells. These observations exhibited a obvious biphasic differentiated (epithelial and mesenchymal) nature of tumor cells, and indicated that adenomatoid tumors were of mesothelial origin. In differential diagnosis, adenomatoid tumor should be distinqushed from epithelioid (histocytoid) hemangioma and adenocarcinoma in epididymis.