X刀治疗脑胶质瘤的方法及结果分析

Methodology and efficacy analysis of Linac-based radiosurgery for brain gliomas

本文报告了我院从1995年3月到1996年5月，采用德国BrainScanX刀治疗系统治疗脑胶质瘤病人45例，经过6～12个月的随访，结果表明，总的治疗有效率达到75．56％，半年以上的生存率为77．78％，颅内压增高等严重并发症的发生率为22．22％。作者总结了适应症选择的标准、治疗计划设计优化的原则、疗效判断标准、X刀后病理和影像变化的特声、以及与并发症发生有关因素等方面的经验和体会。

From March 1995 to May 1996, 45 cases of brain gliomas were treated by stereotactic radiosurgery(SRS) with a modified linear accelerator (BrainScan Xknife treatment system, Germany). The results of being followed up for more than 6 months showed that 75. 56 percent tumors had been controlled growth, The patient'survival rate over 6 months was 77.78 percent. Significant complication occurred in 22. 22 percent cases after treatment. The author summarized and introduced their experience on indication, requirement of Computed Tomography, design and optimization, creterion of therapeutically effect, change of pathology, prevention and cure for complication.