中药骨康对绝经后骨质疏松症骨质量改善的临床观察

Clinical Observation of Gukang on Bone Quality in Postmenopausal Osteoporosis Patients

目的:观察中药骨康对绝经后骨质疏松症骨质量的改善。方法:将70例患者随机分为治疗组、对照组两组,疗程为个6月。治疗组服用中药骨康口服液,共33例,对照组服用固邦,共37例。观察并测定骨质量的改善。结果:两组疗效无明显差异。但治疗组与对照组治疗后肾阳虚主要症状积分值及肾阳虚证总积分比较差异有统计学意义(P<0.01),说明治疗组改善肾阳虚症状疗效优于对照组。治疗组与对照组疗后雌二醇值比较差异有统计学意义(P<0.01),治疗组血中雌二醇水平升高说明骨康冲剂具有类雌激素样作用。结论:骨康和固邦均有治疗骨质疏松症作用,而且骨康效果较好。

Objective：To observe the effect of Gukang on bone quality in postmenopausal osteoporosis patients. Methods： Seventy patients were randomly divided into treatment group （33 cases） and control group （37 cases）. Patients in the two groups were treated with Gukang and Gubang for 6 months, respectively. Bone quality was observed before and after treatment. Results： There was no significant difference between the two groups in effectiveness. However, significant difference existed between the two groups in the main and total symptomatic scores of kidney-yang deficiency （P〈0.01）, indicating that Gukang had better efficacy than Gubang in improving symptoms of kidney--yang deficiency （P〈0.01）. Also, there was remarkable difference in estradiol level between the two groups （P〈0.01）. Increased estradiol level in treatment group showed that Gukang had hormonelike function similar to estrogen. Conclusion： Both being effective for postmenopausal osteoporosis, Gukang has better efficacy than Gubang does.