紫外线照射充氧自血回输治疗重型颅脑损伤合并低氧血症

Clinical study of ultraviolet blood irradiation and oxygenation for severe brain injury and hypoxemia

目的:寻求有效治疗方法,进一步减少颅脑损伤患者致残率及死亡率。方法:将65例重型颅脑损伤(GCS≤8分)合并低氧血症患者分为两组,对照组采用常规治疗,紫外线充氧自血回输治疗(U-BIO)组在常规治疗基础上于入院后1,3,5,7天加用 UBIO 治疗。动态观察患者伤后7天内动脉血氧分压(PaO_2)、血氧饱和度(SaO_2)、肺泡动脉氧压差[P(A-a)O_2],并于伤后1个月进行疗效评定。结果:伤后1,3,7天,UBIO 组 PaO_2、SaO_2明显高于对照组,P(A-a)O_2明显低于对照组,恢复良好率高于对照组。结论:UBIO 疗法能改善颅脑损伤患者低氧血症状态,改善患者预后。

Objective:The paper is to seek an effective therapy for severe brain injury and hypoxemi- a,so as to reduce the disability and mortality.Methods:65 cases with severe brain injury and hypoxemia were divided into the treatment group and control group.The control group were only treated with con- ventional medications.The treatment group were treated with the conventional medications plus ultravi- olet blood irradiation and oxygenation (UBIO).The UBIO was given at 1th,3rd,5th,7th day of posthospitalization.Within 7 days after brain injury,the PaO_2,SaO_2 and P (A-a)O_2 were determined. While the effects were assessed after 1 month of injury.Results:In UBIO group,the value of PaO_2, SaO_2 was obviously higher than that of control group,the P(A-a)O_2 was lower than that of control group.At the same time,the clinical effects of UBIO group were also better than the control group.Con- clusions:These findings show that UBIO treatment can rapidly improve the symptoms of hypoxemia and brain injury.It is beneficial to patient's prognosis.