体外射频热疗治疗前列腺增生症

Extracorporeal radiofequency hyperthermia for prostatic hyperplasia

目的:探讨体外射频热疗治疗前列腺增生症的疗效、并发症及影响疗效的因素。方法:应用体外射频热疗法治疗前列腺增生症(BPH)患者60例.温度在42℃左右,时间120分钟,一次完成。随访热疗前后不同时期的临床症状评分,尿流率等的改善,并分析病程、前列腺体积、治疗前临床症状严重程度、尿流率等因素对疗效的影响。结果:热疗前症状评分平均15分,热疗后2～4周及8～12周均为5分;总下降分数均为7分;下降幅度分别为63.6%和54.5%。早期梗阻症状改善优于刺激症状,后期则相反。最大尿流率(MFR)及平均尿流率(AFR)明显改善.有统计学意义。结论:此温度条件下的热疗,可缓解BPH 的临床症状,有限的改善尿流率,但疗效随热疗后时间延长而下降。认为目前温度条件下的射频热疗,可作为手术绝对禁忌患者的一种补充治疗手段。

Objective:In order to explore the effects of extracorporeal radiofrequency (RF) hyper- thermia on benign prostatic hyperplasia and its complications as well as the influenced factor to efficacy. Methods:60 cases with benign prostatic hyperplasia were managed with extracoporeal RF therapy,the hyperthermia time was 120 rain,one time and the temperature was about 42℃,The relationship among the course of disease,prostatic size,severity,urine flow rate and effects was analysed.The clinical symptoms were evaluated by Madson score method,the urine flow rate was determined by Type-1000 Urodyn apparatus,the prostatic gland was examined by B-uhrasonos-cope.After treatment,the fol- low-up was performed.Results:The Madson score was respectively reduced 63.6% and 54.50% at 2～ 4 weeks and 8～12 weeks of post-treatment.The urine flow rate was obvioosly improved.Conclusion: It is demonstrated that the RF therapy may be a supplementary treatment for patients having surgical contraindication.