慢性肺心病急发期血清结合胆酸、铁蛋白和透明质酸的变化

The Changes of Serum CG、Fer and Ha in Cor Pulmonale with Acute Exacerbation

采用放射免疫测定法测定了６２例慢性肺心病急发期患者（轻度２０例，中度２６例，重度１６例）的血清结合胆酸、铁蛋白、透明质酸浓度，同时还做了血清白蛋白的检验。其结果显示血清结合胆酸、铁蛋白、透明质酸随着病情的加重而升高（Ｐ＜０．００１），而白蛋白越低，病情越重（Ｐ＜０．００１）。血清结合胆酸与铁蛋白有明显正相关（ｎ＝６２，ＰＲ＝０．２９２２，Ｐ＜０．０５），但与透明质酸和白蛋白无相关性。认为血清结合胆酸和铁蛋白对于肺心病急发期肝功能损害的诊断是较敏感和有价值的，而血清透明质酸和白蛋白是不可靠的。

The serum conjugatedcholic acid(CG),ferritin(Fer) and hyaluronic acid(HA)in 62 patients(mild,n=20;moderate,n=26;severe,n=16)with cor ulmonale durign acute exacerbation were measured by means of RIA,atthe samw time their serum albumin(Alb)was tested.The results showed that the higher the levels of serum CG,Fer and HA,as well as the lowerthe level of serum Alb,the severer the disease(P<0.001);and that CG is obviulsy correlated with Fer)n=62,PR=0.2922<0.05)and without HA or Alb.The Conclusion is that the serum CG and Fer are valuable to diagnose liver damage in cor pulmnale with acute exacerbation,but the serum HA and Alb are not.