恶性滋养细胞肿瘤解剖分期和预后评分的临床意义

Clinical significance of the anatomical stage and the prognosis score of GTT

目的回顾性分析评价FIGO解剖分期和预后评分在GTT治疗中的临床意义。方法选择有比较完整临床资料的已治GTT患者90例,根据2000年FIGO分期和评分标准,进行解剖分期和预后评分,并据此比较治疗的效果。结果绒癌组高危比例37.8%,侵蚀性葡萄胎组高危比例17.3%。解剖分期为Ⅰ期和Ⅲ期的低危组患者疗效好于同期高危组患者(P<0.05)。在复发的6例患者中,1例为低危,5例属高危者。给予综合治疗的17例疗效满意。结论绒癌患者存在高危因素者多于侵蚀性葡萄胎。在同期别中,低危患者疗效要好于高危者。治疗时应同时参考解剖分期和预后评分并有效利用综合治疗。

Objective To analyse and evaluate the clinical significance of FIGO stage and prognosis score in the treatment of gestational trophoblastic tumor（GTT）. Methods Ninety cases who had complete data, and had been treated were selected. They were given anatomical staging and prognosis score. The efficacy of treatment was compared, according to 2000 FIGO stage and score standard. Results The proportion of high risk was 37. 8% in choriocarcinoma and 17. 3% in infiltrating hydatidiform mole. The efficacy of treatment in stages Ⅰ and Ⅲ of the low risk group was better than the high risk group at same stage （P 〈 0. 05 ）. In 6 cases of recur rence, one belonged to low risk and 5 belonged to high risk. The efficacy of comprehensive treatment was satisfactory in 17 cases. Conclusion The high risk factors for choriocarcinoma are more numerous than those for infiltrating hydatidiform mole. At same stage the treatment effectiveness in patients with low risk is better than that in patients with high risk. The anatomical stage and prognosis score should be used as reference, and comprehensive treatment should be used effectively.