硬膜外注用吗啡加氟哌啶超前镇痛

PREEMPTIVE ANALGESIA WITH EPIDURAL COMBINATION OF MORPHINE AND DROPERIDOL

选择60例在连硬麻醉下施行择期腹部手术的病人，随机等分为三组，在硬膜外注入局麻药获得满意的麻醉平面后，于手术前分别硬膜外注入生理盐水、吗啡4mg或吗啡4mg加氟哌啶2．5mg，结果手术前超前硬膜外注入吗啡或吗啡加氟哌啶均能产生良好的镇痛效果，而硬膜外注用吗啡时加用氟哌啶，不仅增强吗啡的镇痛效果，而且还能显著减少与硬膜外吗啡相关的副作用。

60 patients undergoing abdominal surgery under continuous epidural anesthesia were allocated randomly to receive epidurally Saline (group Ⅰ), Morphine 4mg(group Ⅱ) or combination of morphine 4mg and droperidol 2. 5mg (group Ⅲ) before surgery. The results showed that patients received epidurally morphine or combination.of morphine and droperidol can achieve satisfactory postoperative analgesia. Epidural administration of combination of morphine and droperidol not only improved postoperative analgesia of morphine, but also reduced significantly epidural morphine related side effects.