高血压与脑血管梗塞病人血液流变学与脑血液动力学的相关性研究

THE CORRELATIVE STUDY BETWEEN HEMORHEOLOGY AND HEMODYNAMICS OF PATIENTS WITH HYPERTENSION AND CEREBRAL INFARCTION

脑血液动力学与血液流变学的相关性研究对于脑血管疾病的诊断治疗具有重要的意义。本研究通过对高血压、脑血管梗塞及其他非心脑血管病病人的血液流变学与脑血液动力学指标相关性分析表明,脑血液动力学参数受红细胞压积的影响最大,且与全血高切粘度、血浆粘度、全血低切粘度、红细胞聚集指数、血沉等血液流变学指标也有明显的相关性。红细胞压积对脑血液动力学诸参数影响大小的程度依次为动脉舒张压、血管扩张度、脑血管外周阻力、临界压力、脑动脉脉搏波波速。脑血液动力学与血夜流变学两组指标相比,脑血液动力学指标在反映高血压与脑血管梗塞的病理性变化方面更为明显。

It is important about the correlative study between hemorheology and cerebral heraodynamics forthe diagnosis and teatment of cerebral vascular diseases. The results of the correlative study on thepatients with hypertension.cerebral infarction and non-cardio-vascular disease in this study haveshowed that, the parameters of cerebral hemodynamics are obviousely affected by the hematocrit,these parameters are also correlative with other hemorheologic parameter-high shear stressviscosity of whole blood, plasma viscosity, low shear stress viscosity of whole blood, erythrocyteaggregation index, erythrocyte sedimentation.The effect degree of hematocrit on the cerebralhemodynamics parameters is diastolic pressure, dilation index of blood vessels, cerebral vascularresistance,critical pressure, transmission velocity of waves in cerbral artery from high to low. Thecomparison of parameters between cerebral hemodynamics and emorheology show that the former iscloser than the later on the correlative with the pathologic changes of hypertension and cerebral infarction.