门冬胰岛素强化治疗2型糖尿病疗效观察

Study of Insulin Aspart in Intensification Therapy on Type 2 Diabetes Mellitus

目的:观察超短效人胰岛素类似物与短效人胰岛素诺和灵R(Novolin R)强化治疗2型糖尿病的疗效差异。方法:将90例2型糖尿病病人随机分为2组,进行胰岛素泵持续皮下输注治疗两周,观察两组治疗前后血糖值,血糖达标时间,胰岛素用量,低血糖发生率。结果:门冬胰岛素(insulin aspart)组与诺和灵R组血糖得到同样程度的改善,但门冬胰岛素组血糖达标时间短,胰岛素用量少,两组均无低血糖发生。结论:门冬胰岛素在胰岛素泵强化降糖治疗更具优势。

Objective ： To observe the difference of therapeutic effect between supershort-effect insulin aspart and short-effect insulin novolin R on diabetes patients. Method： ninety patients with type 2 diabetes mellitus were divided into two groups radomly and received insulin pump therapy for 2 weeks. The blood glucose before and after therapy, period Of reached target, total insulin dosage and whether hyposlycemia happened were observed. Result： Period of reaching target of aspart group was shorter than novolin R group and total insulin dosage was less than novolin R group. There were no hypoglycaemia happened in neither group. Conclusion ： Insulin aspart has superiority than novolin R in insulin pump intensification therapy to decrease blood sugar.