肿瘤坏死因子和C反应蛋白预测急性心肌梗死泵功能的意义

Prognostic Value of C-Reactive Protein and Tumor Necrosis Factor for Cardiac Dysfunction in Acute Myocardial Infarction

本文观察了82例急性心肌梗死（AMI）患者泵功能与肿瘤坏死因子（TNF）和C反应蛋白（CRP）的关系。结果提示，TNF的高低与AMI泵功能分级无相关性，巨在AMI发病36小时内迅速消失；CRP与AMI泵功能不全呈显著负相关，当CRP＞52500μg／L时，左室射血分数＜0．35。

The serum levels of C-reactive protein (CRP) and tumor necrosis factor (TNF) were dynamically measured in 82 patients with acute myocardial infarction (AMI). The results showed that TNF level was not correlated with the cardiac function in AMI. CRP level was negatively correlated with the cardiac function (r=0. 94, P< 0. 05 ). When CRP level was more than 52500μg/L, the left ventricular eject fration was less than 0. 35.