白念珠菌生物膜的研究

Progress in the research of Candida albicans biofilms

细菌生物膜相关感染发病率不断上升,且治疗困难,已受到广泛的关注。对于真菌,生物膜以及生物膜在真菌感染与耐药性产生过程中的作用只是近年来才受到国内外学者与临床专家的关注,目前的研究多集中在念珠菌属。本文综述了白念珠菌生物膜的形成与特征、影响因素、耐药性的分子机制等几方面内容。

Infections associated with bacterial biofilms have been studied extensively for its high incidence and its difficulty of treatment. While the fungal biofilms interrelate with infection, its role in drug resistance are drawing scientists＇ attention worldwide. Now most of the researches are focused on Candida spp. This paper reviewed and summarized the research progress of biofilm＇s formulation, characteristics, influencing factors, molecular mechanism in resistance of Candida albicans.