女性下生殖道支原体存在情况及与疾病关系

THE EXISTENCE AND PATHOGENICITY OF MYCOPLASMA IN FEMALE GENITOURINARY TRACK

目的利用rDNA序列对女性人群下生殖道中的支原体进行检测与分型,并初步探讨支原体与女性下生殖道疾病的关系。方法选择妇女保健门诊健康体检女性、孕早中期妇女,以及妇科门诊病人190例,收集阴道分泌物采用PCR-RELF法进行支原体检测及详细分型。结果190例女性阴道分泌物中检测解脲支原体(Uu)阳性39例(20.53%),人型支原体(Mh)阳性52例(27.37%),Uu、Mh同时阳性26例(13.68%);支原体阳性率与研究对象的年龄,阴道炎、宫颈炎的发病,妊娠、绝经状态无关(P>0.05)。结论Uu和Mh是女性下生殖道共生菌,它可以正常存在而不导致疾病。

Objective To detect and group mycoplasma in genitourinary track and investigate its pathogenicity in female crowd by rDNA array. Methods Samples of vaginal discharge in 190 normal women were collected from gynecology clinic, detection and grouping for mycoplasma were done by PCR-RFLP method. Results Of 190 samples, ureaplasma urealyticum （Uu） positive 39 （20.53%） ; mycoplasma hominis （Mh） positive 52 （27.37%） ; both Uu and Mh positive 26 （13. 68%）. The positive rates of Uu and Mh were not correlated with age, vaginitis, cervicitis, pregnancy, or menopause （P〉0.08）. Conclusion Uu and Mh are symbiotic in female genitourinary track, which may normally exist without causing any disease.