摘要
目的了解肿瘤病人心理状况与免疫功能及医院感染的关系。方法对89例肿瘤病人进行前瞻性心理测试,按测试结果将56例抑郁者和33例非抑郁者分别设为观察组和对照组,比较两组病人非特异性免疫指标、放射免疫指标及细胞免疫指标,并对医院感染情况进行分析。结果两组病人非特异性免疫指标、放射免疫指标及CD4指标比较差异均有显著性（t=2.19-6.78,P〈0.05）。两组医院感染率比较差异有显著性（χ^2=4.02,P〈0.05）。结论肿瘤抑郁病人特异性及非特异性免疫功能受损,容易因自身免疫功能降低而引发院内感染。
Objective To investigate the relationship between the psychologic status, immune function and nosoeomial infection in tumor patients. Methods A prospective psychologic test and measurment was done in 89 tumor patients, who were divided into depression group （56 eases） and non-depression group （33 cases）. Nonspecific immunity index, radioimmunity index, cellular immunity index and hospital-acquired infection were compared between the two groups. Results The difference of the indeces of above items between the two groups was significant （t=2.19-6.78,P〈0.05）, and the incidence of infection was also significant （Χ^2= 4.02,P〈0.05）. Conclusion The immune function of tumor patients is damaged, they are then easy to get nosocomial infection.
出处
《青岛大学医学院学报》
CAS
2008年第6期545-546,共2页
Acta Academiae Medicinae Qingdao Universitatis
关键词
肿瘤
心理测定学
免疫减弱宿主
交叉感染
Neoplasms
Psychometrics
Immunocompromised host
Cross infection
