内蒙古自治区城镇新生儿乙型肝炎疫苗接种率及免疫效果调查

INVESTIGATION ON IMMUNIZATION COVERAGE RATE AND IMMUNE EFFECT OF HEPATITIS B VICCINE IN NEWBORNS IN CITIES AND TOWNS OF INNER MONGOLIAN AUTONOMOUS REGION

为了解内蒙古自治区城镇新生儿乙型肝炎（乙肝）疫苗的接种率及免疫效果，１９９５年４月，采用批质量保证抽样法（ＬＱＡＳ）进行了抽样调查。抽检的２２个城镇中，乙肝疫苗接种率≥８５％的１４个，８０％的４个，７０％的１个，６５％的３个；及时接种率偏低，仅赤峰市的２个区达到８５％。６３３名儿童乙肝疫苗全程３针免疫１个月后采血，放射免疫法测定，ＨＢｓＡｇ阳性率为１９０％，抗－ＨＢｓ阳性率８９２６％，抗－ＨＢｃ阳性率８０６％。说明抗－ＨＢｓ显著上升，ＨＢｓＡｇ和抗－ＨＢｃ明显下降。

For the purpose of investigating the immunization coverage rate and immunee ffect of hepatitis B(HB) vaccine in the newborns in cities and towns of Inner Mongolian Autonomous Region,the Lot Quality Assurance Sampling(LQAS)method was adopted at the time of April,1995 Among 22 cities and towns investigated the immunization coverage rate of HB vaccine was ≥85% in 14 cities,80% in 4 cities,70% in 1 city and 65% in 3 cities;the timely coverage rate was much more lower and only two disricts of Chifeng city reached 89%.The serum markers were detected in 633 infants one month after the whole coourse (3 injections) of vaccinatik by RIA technique ,The nositive rate for HBsAg was 1 9%,for anti-HBs was 89 26%,for anti-HBc was 8 06%,showing that there was a notable rising of anti-HBs and a marked decreasing of anti-HBc and HBsAg.