饲料防霉剂富马酸二甲酯微波合成研究

Synthesis of Preservative for Feed-Dimethyl Fumarate by Microwave Radiation

以马来酸酐和甲醇为原料用微波辐射的方法一步合成富马酸二甲酯.结果表明,此方法反应时间短,产率达87.1%.最佳反应条件为:微波辐射功率480 W,催化剂硫酸用量为6%,盐酸用量为10%,醇酐物质的量比为6∶1,微波辐射时间20 min.

Dimethyl Fumarate is synthesized by esterification of maleic anhydride and methanol under microwave radiation on one-step method. The results show the nethod has the advantage of less reactron time,and under optimal conditions, the yield of the product could reach 87.1%. The optimal conditions are as follows, power of microwave radiation：480 W, Catalyst：H2SO4 6% , HCI：10% , molar ratio of alcohol to anhydride 6 ： 1, microwave radiation time： 20 min.