口服山莨菪碱佐治婴幼儿轮状病毒肠炎120例疗效观察

Observations of Curative Effects-120 Cases of Treating Infants’ Duo Virus Enteritis by Taking Anisodamine(654-2 )Orally

目的观察口服山莨菪碱佐治婴幼儿轮状病毒肠炎的临床疗效。方法对照组98例采用补液、抗病毒、口服思密达、合理饮食、对症治疗,疗程5～7天;治疗组120例在上述基础上口服山莨菪碱(654-2){0.15mg-0.2mg}/kg.次.tid,疗程5～7天。结果治疗组120例中显效86例(72%),有效30例(25%),无效4例(3%),总有效率97%;对照组98例中,显效26例(27%),有效46例(47%),无效26例(27%),总有效率73%,治疗组与对照组比较具有显著差异性(X2=24.72,P<0.01)。结论口服山莨菪碱(654-2)片佐治婴幼儿轮状病毒肠炎有明显疗效。

Objective Observing the clinic curative effects by taking anisodamine （654-2） orally for treatment of infants＇ duo virus enteritis. Methods Control group with 98 cases： fluid replacement, anti-virus, reasonable diet and symptomatic treatment. Course of treatment： 5-7 days. Treatment group with 120 cases： take anisodamine （654-2）{0.15mg 0.2mg}/kg： time. Course of treatment： 5-7 days. Results in treatment group with 120 cases, obviously effective for 86 cases （72%）, effective for 30 cases （25%）, invalid for 4 cases （3%）, total effective percentage is 98%. In control group with 98 cases, obviously effective for 26 cases （27%）, effective for 46 cases （47%）, invalid for 26 cases （27%）, total effective percentage is 73%. There is great discrepancy between control group and treatment group （X^2=24.72,P〈0.01）. Conclusion it＇s very effective to treat infants＇ duo virus enteritis by taking anisodamine （654-2） orally.