经尿道前列腺电切术对老年良性前列腺增生症患者生活质量的影响

Effect of transurethral resection of prostate on quality of life in aged patients with benign prostatic hyperplasia

目的:探讨经尿道前列腺电切术(transurethral resection of prostate,TURP)对老年良性前列腺增生症(benign prostatic hyperplasia,BPH)患者生活质量(quality of life,QOL)的影响。方法:对358例老年BPH患者TURP术前及术后3月进行国际前列腺症状评分(International Prostate Symptom Score,IPSS)、勃起功能国际问卷(The 5-Item Version of the International Index of Erectile Function,IIEF-5)、生活质量评分(Quality of Life Scale,QOLS)、焦虑自评量表(Self-Rating Anxiety Scale,SAS)、抑郁自评量表(Self-rating Depression Scale,SDS)评估,同时检测最大尿流率(maximum flow rate,Qmax)和剩余尿量(residual urine volume,RUV)。结果:术后3月与术前比较,患者的IPSS,QOLS,SAS和SDS评分以及RUV显著性减少,Qmax显著性增高,但反映性功能指标的IIEF-5评分治疗前、后无统计学差异。结论:TURP能显著缓解老年BPH患者症状,显著改善患者的QOL;TURP对性功能的改善没有帮助。

Objective To investigate the effect of transurethral resection of prostate （TURP） on the quality of life in aged patients with benign prostatic hyperplasia （BPH）. Methods Altogether 358 BPH patients were evaluated by International Prostate Symptom Score （IPSS） , the 5-Item Version of the International Index of Erectile Function （ IIEF-5 ） , Quality of Life Scale （ QOLS ） questionnaires, Self-Rating Anxiety Scale （SAS）, Self-Rating Depression Scale （SDS）, residual urine volume （ RUV ） , and maximum flow rate （ Qmax ） before and at 3 months after they underwent TURP. Results The mean scores of IPSS, QOLS, SAS, and SDS, and mean RUV decreased, and mean Qmax increased significantly at 3 months after receiving operation compared with those before the treatment in aged patients with BPH. But no significant difference was found in the scores of IIEF-5 between post-operation and pre-operation. Conclusion TURP may alleviate BPH clinical symptoms and improve quality of life, but may not be helpful to the recovery of sexual function in aged patients with BPH.