一起发生在新生儿重症监护病房的肺炎克雷伯杆菌败血症调查

A Case of Klebsiella pneumoniae Outbreak in a Newborn Intensive Care Unit

目的对一起发生在某医院新生儿重症监护病房(NICU)的群体性肺炎克雷伯杆菌败血症进行调查和分析。方法采用现场流行病学调查方法,对标本进行细菌培养和菌株同源性检测。结果共报告病例4例,均为NICU患儿,所有患儿同期咽拭子、肛拭子培养均为肺炎克雷伯杆菌。环境采样发现4株肺炎克雷伯杆菌,同源性鉴定结果显示所有肺炎克雷伯杆菌菌株高度同源。经强化医务人员手卫生、彻底环境清洁后,疫情得到控制。结论本次NICU内的败血症暴发疫情由肺炎克雷伯杆菌引起,可能是通过医务人员的手进行传播。

Objective To investigate and take a case study on a Klebsiella pneumoniae outbreak in a newborn intensive care unit （NICU）. Methods Using epidemiological investigation method to cultivate bacilli and detect the homology. Results Klebsiella pneumonia was detected in 4 NICU patients . Based on environmental sample analyses, four Klebsiella pneumonia strains were identified and confirmed to be highly homologous. The outbreak was effectively controlled after the strict implementation of hand hygiene practice and environment disinfection. Conclusion Klebsiella pneumonia outbreak in NCIU may be caused by the route of hand transmission.