米非司酮治疗异位妊娠60例分析

Analysis of efficacy of mifepristone in treatment of 60 patients with ectopic pregnancy

目的观察60例异位妊娠患者应用米非司酮保守治疗的疗效。方法回顾性分析60例确诊为异位妊娠的患者,口服米非司酮100mg,2次/d,共3d,服药结束后判断疗效。结果治愈54例(90%),未愈6例(10%)。盆腔包块≤5cm且β人绒毛膜促性腺激素(β-HCG)≤2000U/L时治愈成功率较高。结论大剂量米非司酮治疗异位妊娠具有简便、安全、无毒副作用等优点,是异位妊娠保守治疗的一种较好方法。适合于生命体征平稳,无剧烈腹痛,血β-HCG≤2000U/L,盆腔包块≤5cm,无胎心搏动及要求保守治疗的早期异位妊娠患者。

Objective To observe the efficacy of mifepristone of 60 patients with ectopic pregnancy. Methods The data of 60 women with ectopic pregnancy were retrospectively analyzed. All of them were administrated with mifepristone 100 mg twice a day for three days. The efficacy was evaluated after the final dose of mifepristone. Results The results of treatment in fifty - four patients were successful （90%） and six with failure （ 10% ）. The successful rate was higher in patients with the size of mass in pelvic cavity≤5 cm and concentration of β - HCG≤2 000 U/L.. Conchlsion High dosage of mifepristone in treatment of ectopic pregnancy is convenient, safe, and no side - effect. It is suitable for patients with early cctopic pregnancy who have smooth life - sign, β - HCG≤2 000 U/L and the size of mass in pelvic cavity≤5 cm, without acute bellyache and pulsation of fetal heart in fallopian tube and patients requesting conservative treatment.