磷酸钙钛生物陶瓷膜诱导HAp沉积的研究

Study of HAp Deposition Induced by CaTi_4(PO_4)_6 Bioceramic Films

为了提高磷酸钙钛(CaTi4(PO4)6,简称CTP)陶瓷膜的生物活性,采用碱液对其进行了处理。研究了碱液的浓度、温度及处理时间对CTP诱导沉积HAp的影响。采用XRD、SEM检测其物相组成和表面形貌。实验结果表明:碱处理液的浓度、处理温度及时间对CTP陶瓷膜表面成分结构和诱导HAp沉积的能力有较大影响;陶瓷膜经浓度为1.0mol/L、温度为80℃的碱溶液处理2h,在仿生溶液中浸泡4d后有明显HAp沉积。说明碱处理对CTP陶瓷膜起到了生物活化改性的作用,有助于诱导HAp沉积,达到了提高生物活性的目的。

In order to improve the bioactivity of CaTi4 （PO4）6 （CTP） ceramic films, the alkali solution is adopted to modify the surface of CTP coating in this paper. The effects of concentration, treating temperature and time of the alkali solution on CaTi4 （PO4）6 ceramic films inducing the deposition of hydroxyapatite（HAp） are studied. The phase composition and the micro-structure are detected by XRD and SEM. The results show that the concentration, treating temperature and time of the alkali solution have great influence on the ceramic films surface components＇ structure and the ability of inducing the deposition of HAp. When the concentration of the alkali solution, treating temperature and time are 1.0mol/L, 80℃ and 2h, respectively, the apparent HAp crystal is deposited on the surface of ceramics film after soaking in biomimetic solution for 4d. It is indicated that CTP ceramic films treated by the alkali solution can induce HAp to deposit in biomimetic solution, and the bioactivity is enhanced.