轻度认知功能障碍患者的神经心理学测试

Neuropsychological examination in patients with mild cognitive impairment

目的探讨轻度认知功能障碍(MCI)患者是否有神经心理方面的损害及损害的特点,以期为早期筛查出MCI患者提供参考指标。方法采用数字颜色连线测验(CTT)、数字广度测试(DS)、词汇流畅性测试(VFT)、中文听觉词汇(CALT)、线段方向判断(JLOT)和Stroop测验对30名MCI患者和30名性别、年龄和教育程度相匹配的正常对照组进行评定。结果MCI患者的CTT、VFT、数字广度倒背和CALT与正常对照组相比差异均有显著性。JLOT、Stroop测验和数字广度顺背成绩虽有所下降,但差异均无显著性。结论MCI患者的神经心理方面有损害。对MCI危险人群进行神经心理学测试能早期筛选出MCI患者。

Objective To explore whether the patients with MCI have neuropsyehological impairments and their neuropsychologieal characteristics. Methods Color trail test （CTT） , digital span （DS） test, verbal fluency test （VFT） , Chinese auditory learning test （CALT）, judgment of line orientation test （JLOT） and Stroop test were applied to evaluate neuropsychologieal characteristics in 30 patients with MCI. The resuhs were cmnpared with those from 30 age-, gender- and educational level - matched normal controls. Results There were significant differences in the CTT, the VET, the backward DS and the CALT tests between the MCI and the control groups. No significant differences were found in the JLOT, the Stroop test and the forward DS tests between the two groups. Conclusions The patients with MCI showed neuropsychologieal impairments. Neuropsychological tests may be useful to early diagnosis of MCI.