宫颈癌前哨淋巴结定位和检测

The Localization and Detection of Sentinel Lymph Node in Cervical Cancer

目的：使用亚甲蓝作为示踪剂检测宫颈癌前哨淋巴结,观察其安全性和可行性。方法：2006年3月至2007年3月,采用亚甲蓝检测25例ⅠB-ⅡB期宫颈癌前哨淋巴结。根据术后病理判断用前哨淋巴结预测盆腔淋巴结转移的准确性和假阴性率。结果：25例中,19例成功定位出前哨淋巴结36枚,总检出率为76.00%。最多见检出部位为闭孔淋巴结。准确率为100.00%,假阴性率为0。结论：染料法宫颈癌前哨淋巴结定位是安全可行的,检出部位以闭孔窝最多见。

To investigate the safety and influential factors on sentinel lymph node（ SLN） detection with rneihylene blue in cervical cancer. Methods： From March 2006 to March 2007, the SLN were detected by rnethylere biue dying in 25 patients with stage ⅠB - Ⅱ B cervical cancer. The accuracy and false negative rate of SLN predicting the pelvic lymph node metastasis were evaluated based on post-operative pathologic examination. Resuits： A total of 36 SLNs were identified successfully in 19 of 25 patients. The total detection rate was 76.00%. The most commonly site of detection was obturator fossa. The accuracy was 100.00%, and false negative rate was 0. Conclusions- SLNs detection for cervical cancer with mebhylene blue is safe and feasible. The most common site of detection is obturator fossa.