摘要
射频消融作为微创治疗的方法之一,为不能行手术切除的肝脏肿瘤提供了有效的治疗手段.多项研究发现射频消融除了可以使肿瘤发生凝固性坏死,还可以促进肿瘤细胞的凋亡,抑制肿瘤的血管生成,增加肿瘤细胞的免疫原性,提高机体的抗肿瘤免疫力.本文简要论述射频消融治疗肝脏肿瘤的生物学机制.
As a minimally invasive therapy, radiofrequency ablation （RFA） is used to cure the unresectable liver cancer. Many investigations demonstrated that RFA can not only result in coagulation necrosis of tumors, but also promote apoptosis of cancer cells, inhibit angiogenesis of carcinoma, improve tumor immunogenicity and elevate antitumor activity of the body. This review discusses the mechanism of RFA in treating liver cancer.
出处
《世界华人消化杂志》
CAS
北大核心
2008年第30期3416-3420,共5页
World Chinese Journal of Digestology
基金
南通市社会发展基金资助项目
No.S2006032~~
关键词
射频消融
肝脏肿瘤
治疗机制
Radio frequency ablation
Liver cancer
Therapeutic mechanism
