环糊精在绿色有机合成中的应用

Application of Cyclodextrins in Green Organic Synthesis

环糊精通过主客体相互作用能将疏水性有机分子转移到对环境友好的水中进行有机反应,还能影响分子的电性环境,使反应在温和的条件下就能获得良好的收率,几乎没有副产物,在绿色有机合成中应用十分广泛。本文就近年来环糊精在绿色有机合成中的应用分为氧化、加成、开环、脱保护、偶联和取代等几种反应类型,并对这些反应进行了概述。

Cyclodextrins, widely applied in green organic synthesis, can transfer hydrophobic molecules into water by the supramolecular interaction. As an important kind of host molecules, they can also influence the microenvironment of hydrophobic molecules by the host-guest interaction and change traditional reaction conditions to obtain good yield without byproduct. The recent developments of application Of cyclodextrins in green organic reactions such as oxidation reaction, addition reaction, ring opening reaction, deprotection reaction, coupling reaction, substitution reaction, etc. are reviewed. The catalytic mechanisms are also discussed in this article.