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辛伐他汀对急性脑梗死患者动脉粥样硬化及血浆C反应蛋白的影响

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摘要 目的观察脑梗死急性期患者应用辛伐他汀后动脉粥样硬化斑块和血浆C反应蛋白的变化。方法对59例患者给予辛伐他汀20 mg,qn,口服。治疗前后查血脂、CRP并测量颈动脉粥样硬化斑块大小,颈内动脉狭窄程度。结果患者治疗2周后,CRP由(10.84±3.4)mg/L降至(3.8±1.8)mg/L(P<0.05),TC由(5.76±1.04)mol/L降至(4.25±1.11)mol/L,TG由(1.96±0.96)mol/L降至(1.45±0.82)ml/L,LDL由(3.65±1.12)ml/L降至(1.80±0.86)ml/L(P<0.05)。治疗3个月后颈内动脉粥样硬化斑块缩小,颈内动脉狭窄程度得到改善。结论辛伐他汀能够在降血脂的同时,减轻炎症反应,稳定动脉粥样硬化斑块,在脑梗死急性期的治疗中具有重要意义。
作者 潘素琴
出处 《中国实用神经疾病杂志》 2008年第11期60-62,共3页 Chinese Journal of Practical Nervous Diseases
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