孕妇糖代谢异常与子痫发病的相关性

Correlation of glycometabolism abnormality and onset of eclamptism in pregnant women

目的探讨妊娠期糖代谢异常与孕妇子痫的关系。方法对产前妊娠检查的250例孕妇,在妊娠24～28周给予口服75g葡萄糖进行糖耐量试验(OGTT)检测,其中餐后1h血糖大于或等于7.8mmol/L的孕妇确认为糖代谢异常,共50例,其余200例为无糖代谢异常孕妇,并对两组结果进行比较。结果妊娠期糖代谢异常孕妇子痫的发病率明显高于妊娠期无糖代谢异常孕妇,二者差异有统计学意义(P<0.05)。结论孕妇进行OGTT有利于掌握其血糖水平,可预测其子痫发生的危险度,并可用于病情监测。

Objective To explore the relationship between glycometabolism abnormality and onset of eclamp- tism in pregnant women. Methods Oral glucose tolerance test （OGTT） was performed on 250 antenatal examined pregnant women at 24-28 gestational weeks. The 50 pregnant women whose 1 h postprandial blood sugar was 7.8 mmol/L or above were assigned as glycometabolism abnormality group~ the other 200 cases as control group. The incidence of eclamptism was compared. Results The incidence of eclamptism of glycometabolism abnormality group was significantly higher than that of control group （P〈0. 05）. Conclusion OGTT of pregnant women conduces to prehension of their blood glucose level, prediction of eclamptism occurrence and monitoring of pathogenetic condition.