双氧水肾盂灌注治疗乳糜尿疗效观察

Treatment of chyluria with Hydrogen peroxide （ H2O2） irrigation of the renal pelvis

目的探讨双氧水肾盂灌注治疗乳糜尿的疗效。方法自1989～2006年本院收治乳糜尿病人102例采用3％双氧水、68例采用1％硝酸银进行肾盂灌注，比较两组患者乳糜尿治愈率及复发率。结果双氧水组乳糜尿消失率为93．14％（95／102），81例（81／95）随访2～12年，治愈率为92．59％（75／81），复发率7．41％（6／81）；硝酸银组乳糜尿消失率为79．41％（54／68），48例（48／54）随访2年～10年，治愈率为75％（36／48），复发率25％（12／48），两组治愈率及复发率分别比较差异非常显著（P〈0．01）。结论双氧水肾盂灌注治疗乳糜尿治愈率高，并发症少，复发率低，不失为一种非手术治疗乳糜尿的可靠方法。

Objectives To evaluate the clinical efficacy of Hydrogen peroxide（ H2O2 ） irrigation of the renal pelvis for the treatment of chyluria. Methods 102 or 68 cases with filarial chyluria in 1989 -2006 were treated with H2O2 or silver nitrate irrigation of the renal pelvis. The response,as judged from the disappearance of chyluria and the incidence of complications, was analyzed. Results The H2O2 irrigation of the renal pelvis groups, the disappearing rate of chyluria was 93.14% ,81 （81/95） cases were followed up for 2 to 12 years,75 cases （92.59%） were found to have been cured and 6 （7.41%） had recurrence; The silver nitrate irrigation of the renal pelvis groups, the disappearing rate of chyluria was 79.41% , 48 （48/54） cases were followed up for 2 to 10 years,36 cases （75%） were found to have been cured and 12 （25 %）had recurrence. The treating effect in the first group is higher than the last group between two groups. Conclusions Treatment of chyluria with H2O2 irrigation of the renal pelvis is a simple and convenient method with certain eff;cacy and no obvious complications occurred. It is an ideal non - surgical procedure for treatment of chyluria.