摘要
小儿实体肿瘤的治疗是提高恶性实体瘤生存率的关键之一。肿瘤的外科处理除挽救生命外,主要考虑到生活质量。化疗是选择有效合理联合应用抗癌药,且副作用小,重点之一是化疗药物耐药性的研究;在儿童中尽量少用放疗,如必需应用,也需注意防护与适当剂量,现介入性治疗和术中放疗已逐渐开展。治疗实体瘤的新措施还包括生物反馈修饰剂、诱导肿瘤分化、靶向药物和单克隆抗体等。
Solid tumors treatment in children is one of the crucial factors to increase the survival rate of malignant tumors. In addition to saving lives, surgical treatment of tumors can also improve quality of life in patients. Chemotherapy is a reasonable choice because of its anti-cancer action with few side effects. The focus is the drug resistance studies of the chemotherapy. Radiotherapy is not recommended in childhood solid tumor treatment. If it is required, protection and appropriate dosage should be paid attention to. Interventional therapy and intraoperative radiotherapy has been gradually carried out. New measures of solid tumor treatment also include biofeedback modifier, induced tumor differentiation, targeting drugs and monoclonal antibodies, etc.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2008年第11期915-917,共3页
Journal of Clinical Pediatrics
关键词
儿童
实体瘤
治疗
children
solid tumor
treatment
