痉瘫丹治疗创伤性痉挛型截瘫临床疗效分析

Clinical Analysis of Jing Tan Dan Treatment of Traumatic Spastic Paraplegia

目的观察痉瘫丹治疗创伤性痉挛型截瘫的临床疗效,并探讨其作用机制。方法将56例痉挛型截瘫患者分为治疗组(28例)和对照组(28例),对照组采用西药常规治疗,治疗组在常规治疗基础上加用中药痉瘫丹,于治疗前后观察临床疗效。结果两组总有效率,治疗组为89.3%,对照组为53.5%,差异有显著性(P<0.05)。治疗组痉挛消失率为57.2%,明显高于对照组的21.4%,差异有显著性(P<0.01)。结论中药痉瘫丹对痉挛型截瘫临床症状有明显改善作用,与常规治疗合用疗效更显著。

Objective To observe Jing Tan Dan treatment of traumatic spastic paraplegia the clinical efficacy, and its mechanism. Methods Total 56 cases of spastic paraplegia patients were divided into treatment group （ n = 28） and control group （28 cases） and the control group using conventional western medicine treatment, the treatment group on the basis of conventional treatment with tradi- tional Chinese medicine plus Jing Tan Dan, observed before and after treatment. Results The total efficiency of the two groups,the treatment group was 89.3% ,53.5% for the control group,there were significant differences （P 〈 0. 05 ）. The total efficiency of the treatment group was 57.2% ,which was significantly higher than the efficiency of 21.4% of the control, the difference was significant （P 〈 0. 01 ）. Conclusion Chinese Jing Tan Dan for spastic paraplegia and a marked improvement in clinical symptoms, combined with conventional treatment efficacy is more obvious.