纳洛酮联合可拉明治疗肺性脑病的临床研究

Clinical Effect of the Naloxone combined with Coramine in pulmonary encephalopathy

目的探讨纳洛酮联合可拉明治疗肺性脑病的临床研究。方法39例肺性脑病患者入选，随机分为三组，一组14例为纳洛酮联合可拉明静脉滴注，一组12例单用可拉明，一组13例单用纳洛酮三组均在控制性吸氧，强有力抗生素抗感染（静脉给药），畅通气道等综合治疗基础之上应用。结果联合组较单用可拉明组有非常显著疗效（P〈0．01），联合组较单用纳洛酮组疗效显著（P〈0．05）。结论纳洛酮联合可拉明治疗肺性脑病疗效确切。

Objective To investigate the Naloxone combined with Coramine in pulmonary encephalopathy of curative effect observation. Methods 39cases were divided randomly into three groups, Joint group （14cases）, Naloxone group （13cases）and Coramine group （12cases）. Three groups in the control oxygen uptake ,the powerful antibiotic anti-infection（ vein for medicine） ,the unimpeded gas channel and so on above the general complex therapy foundation apply. Results Joint group than in single-Coramine group has a very significant effect（P 〈0.01 ） ,Joint group than in single-Naloxone group has significant effect（P 〈0. 05）. Conclusion Naloxone combined with Coramine treatment pulmonary encephalopathy curative effect to be accurate.