冠脉内支架术治疗冠心病80例临床结果分析

Clinical outcome of intracoronary stenting in 80 patients with coronary artery disease

目的分析冠脉内支架术治疗冠心病近、中期疗效及安全性。方法回顾性分析80例冠脉内支架术资料，观察冠脉内支架术的成功率、再狭窄率及主要心脏不良事件（MACE，包括死亡、非致死性心肌梗死和靶病变重建（TLR）术）。结果92处病变植入支架129枚，国产雷帕霉素药物洗脱支架（SES）组89枚，裸金属支架（BMS）组40枚。手术成功率97．5％，2例死亡。两组再狭窄发生率差异具有统计学意义（3．08％vs39．29％，P〈0．01）。两组TLR率差异具有统计学意义（1．54％粥29．63％，P〈0．01）。MACE发生率13．75％。结论冠脉内支架治疗冠心病安全有效，SES较BMS再狭窄率及TRL率近、中期均显著降低。

Objective To observe the therapeutic effect and the security of intracoronary stenting on coronary artery disease in the near future and intermediate stage. Methods In total,80 patients received intracoronary stenting were enrolled in this retrospective study. The rate of successful procedure, restenosis and the major adverse cardiac event [MACE,including death,nonfatal acute myocardial infarct-tion and target lesion revasculariztion （TLR）] were evaluated. Results There were 92 lesions treated with 129 stents. Rapamycin-eluting stents group （ SES ） was 89 stents, bare metal stents （ BMS ） groups was 40 stents. The success rate was 97.5 %. 2 patients died. There were significant difference in the restenosis rate between two groups （3.08% vs 39. 29% ,P 〈0. 01 ）. There were significant difference in the TLR rate between two groups（ 1.54%vs 29. 63% , P 〈 0. 01 ）. The MACE rate was 13.75 %. Conclusion Intracoronary stenting could be used safely and effectively in patients with coronary artery disease. Compared with BMS, the rate of restennosis and TRL decreased significantly in SES.