摘要
1例63岁男性患者既往有癫痫和高血压病史。近3年患者因高血压一直服用硝苯地平缓释片10mg,2次/d。2个月前,因血压控制不佳,加服依那普利20mg/d。首次服用依那普利后8h,患者出现肉眼血尿伴有少量血块,尿常规示潜血(++++)。B超检查排除肾、输尿管、膀胱结石和肿块。停用依那普利,给予对症治疗,血尿消失。患者继续服用硝苯地平片,未再出现上述症状。
A 63-year-old man had a history of epilepsy and hypertension. In recent 3 years, he has been receiving one tablet of sustained-release nifedipine 10 mg twice daily. Enalapril was added to his treatment two months ago due to poorly controlled hypertension. The patient developed gross hematuria with a small amount of blood clots 8 hours after administration of enalapril. Urinalysis showed occult blood ( + + + + ). Renal, urethra or bladder stones and tumors were not determined by B-scan ultrasound. Enalapril was stopped. Symptomatic therapy was given and hematuria disappeared. Sustained-release nifedipine tablets were continued. Above-mentioned symptoms did not recur.
出处
《药物不良反应杂志》
2008年第5期368-368,共1页
Adverse Drug Reactions Journal
关键词
依那普利
血尿
不良反应
enalapril
hematuria
adverse reaction