重度颅脑外伤患者早期高压氧治疗对预后的影响

Effect of hyperbaric oxygen therapy on prognosis of the patients with severe craniocerebral injury

目的:研究早期应用高压氧治疗对重度颅脑损伤患者预后的影响。方法:46例重度颅脑损伤患者按外伤后进行HBO治疗时机分为两组:A组,n=28例,伤后8～30天,B组18例,伤后31～60天,两组患者在入院24h内和接受HBO治疗4周后分别采用Glasgow昏迷(Glasgow coma scal,GCS)评分,6个月后采用Glasgow预后(Glasgow outcome scale,GOS)进行评分。结果:入院6个月后,A组患者的意识和残疾程度改善较B组显著,两组间的GCS和GOS评分比较,差异有统计学意义(P<0.01)。结论:重度颅脑损伤患者在伤后早期接受HBO治疗效果更好。

Objective：To study the effect of early hyperbaric oxygen（HBO） therapy（8-30d） on prognosis of the patients with severe craniocerebral injury. Methods：Forty six with severe cranioeerebral injury were divided into group A （within 4 week） and B （30-60d） according to the HBO therapy time. GCS scores were assessed within 24h before and 4 weeks after receiving HBO treatment. Glasgow outcome scale （GOS） was used to assess the patients 6 months after HBO treatment. Results：GCS scores were significantly higher in group A than those in control group （p〈0.05）. Six months after severe craniocerebral injury GOS grade in HBO group was better than that in control group （p〈0.05） Conclusion： Early HBO therapy to patients with severe cranioeerebral injury achieves better effects.