亲属活体肾移植48例报告

A Report of 48 Patients with Living-related Donor Kidney Transplantation

目的探讨活体肾移植的供受者选择标准、治疗方法和随访结果.方法分析1998年3月至2008年7月我院实施的48例亲属活体肾移植的供受者临床资料、评估、配型、手术方法及免疫抑制剂方案.结果全部供者术后未出现并发症,术后肾功能正常.48例受者中有不同程度的排斥反应、移植肾功能延迟恢复、感染等并发症.结论亲属活体肾移植排斥反应明显低于尸体肾移植,具有经济、移植肾长期存活效果好的优势,但同时也存在一些伦理学的争议.

Objective To evaluate the standard of choose living-related donors, method of therapy and effect of follow up recipients with livingrelated donor kidney transplantation. Methods This study involved 48 patients and donors from March 1998 to July 2008. Our experience in the clinical material, appraisal, tissue matching, method of operation, and post-transplantation immunosuppressive regime was analyzed. Results All the living-related donors underwent nephrectomy without any complication and the kidney function was normal. 48 recipients had some varying degree complications, such as repel response, delayed recovery of transplant kid- ney, function, infection and so on. Conclusion Compared with the corpse donor kidney transplantation, living-related donor kidney transplantation has littler acute rejection and infection, which can take little money, and might improve the long term graft survival, simultaneously also has some dispute of ethics.