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改良非压迫性腰椎间盘突出大鼠模型的建立 被引量:3

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摘要 本研究旨在建立一种改良非压迫性腰椎间盘突出大鼠模型,现报道如下。 一、材料与方法 1.实验动物和分组:选择8月龄SD清洁级雄性大鼠30只(中山大学动物实验中心提供),体重180—250g,随机分为传统组(10只)、假手术组(10只)和改良组(10只)。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2008年第11期1495-1495,共1页 Chinese Journal of Experimental Surgery
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  • 1李小川,吕刚,金明熙,屠冠军,常楚,谢林.胰岛素样生长因子1抑制人椎间盘细胞凋亡及促进基质代谢的研究[J].中华实验外科杂志,2004,21(7):880-880. 被引量:7
  • 2Schneiderman G, Flannigan B, Kingston S, et al. Magnetic resonance imaging in the diagnosis of disc degeneration: Correlation with discography. Spine, 1987,12:276-281.
  • 3Zhou YL, Lin GF, Baarsch MJ, et al. Interleukin 4 suppresses inflammatory cytokine gene transcription in porcine macrophages. J Leukoc Biol,1994, 56:507-513.
  • 4Schmidt Weber C B, Alexander S I, Henault L E, et al. IL 4 enhances IL 10 gene expression in murine Th2 cells in the absence of TCR engagement. J Immunol, 1999, 162: 238-244.
  • 5Karppinen J, Korhonen T, Malmivaara A, et al. Tumor necrosis factor n αmonoclonal antibody, infliximab, used to manage severe sciatica. Spine,2003, 28:750-754.
  • 6Zimmermann M.Pathobiology of neuropathic pain.Eur J Pharmacol,2001,429:23 -37.
  • 7Devor M,Wall,PD,Catalan N.Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction.Pain,1992,48:261 - 268.
  • 8Woolf CJ,Shortland P,Coggeshall RE.Peripheral nerve injury triggers central sprouting of myelinated afferents.Nature,1992,355:75 - 78.
  • 9Li L,Xian CJ,Zhong JH,et al.Effect of lumbar 5ventral root transection on pain behaviors:a novel rat model for neuropathic pain without axotomy of primary sensory neurons.Exp Neurol,2002,175:23 - 34.
  • 10Sheth RN,Dorsi M J,Li Y,et al.Mechanical hyperalgesia after an L5 ventral rhizotomy or an L5 ganglionectomy in the rat.Pain,2002,96:63 -72.

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  • 1Herlaar E,Brown Z.p38 MAPK signalling cascades in inflammatory disease[J].Mol Med Today,1999,5(10):439-447.
  • 2Jin SX,Zhuang ZY,Woolf CJ,et al.p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain[J].J Neurosci,2003,23(10):4017-4022.
  • 3Weinstein J,Pope M,Schmidt R,et al.Neuropharmacologic effects of vibration on the dorsal root ganglion:an animal model[J].Spine,1988,13(5):521-525.
  • 4Chaplan SR,Bach FW,Pogrel JW,et al.Quantitative assessment of tactile allodynia in the rat paw[J].J Neurosci Methods,1994,53:55-63.
  • 5Denis M,Saloua M,Isabelle G,et al.Pat-hophysiology of disk-related sciatica(Ⅰ):evidence supporting a chemical component[J].Joint Bone Spine,2006,73(2):151-158.
  • 6Olmarker K,Blomquist J,Str(o)mberg J,et al.Inflammatogenic properties of nucleus pulposus[J].Spine,1995,20(6):665-669.
  • 7Kang JD,Georgescu HI,McIntyre-Larkin L,et al.Herniated lumbar intervertebral discs spontaneously produce matrix metalloproteinases,nitric oxide,interleukin-6,and prostaglandin E2[J].Spine,1996,21(3):271-277.
  • 8Hanns UZ.Prostanoids in nociception and pain[J].Biochemical Pharmacology,2007,73(2):165-174.
  • 9Miyamoto H,Saura R,Doita M,et al.The role of cyclooxygenase-2 in lumbar disc herniation[J].Spine,2002,27(22):2477-2483.
  • 10Obata T,Brown GE,Yaffe MB.MAP kinase pathways activated by stress:the p38MAPK pathway[J].Crit Care Med,2000,28(4):67-77.

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