活血化瘀中药治疗腹部手术后并发急性肺损害的疗效观察

Clinical Study on Treatment of Acute Lung Injury after Abdominal Surgical Operations Treated with Huoxue Huayu Herbs

本文对具有急性肺损害症状的４４例腹部手术后患者的多项临床生理指标进行了分析，并早期用活血化瘀药物进行治疗。结果表明，中药治疗二天后ＳａＯ２和ＰａＯ２明显改善，与给药前比较有明显差异（Ｐ＜０．０５），连续给药四天，ＳａＯ２、ＰａＯ２、胸部Ｘ线和综合生理指标显著好转，ＰＧＦ１ａ、ＴＸＢ２、ＣＲＰ、ＲＢＣ－Ｃ３ｂ与给药前比较有非常显著的差异（Ｐ＜０．０１）．其综合生理指标已基本恢复至正常水平。应用中药五天后患者各项观测指标均已恢复正常范围，综合生理指标良好。

Fourty four cases of acute lung injury (ALI) following abdominal surgical operations were treated with Huoxue Huayu (HXHY)herbs.Chinese herbs were administered for seven days.The blood SaO 2 and PaO 2,Plasma TXB 2 and PGF 1a ,RBC C 3b,serum CRP and chest X ray were observed on these patients.Results showed that SaO 2 and PaO 2 wrer improved after 2 days treatment in the sixth day,the SaO 2,PaO 2,X ray,PGFla,TXB 2,CRP,RBC C 3b and clinical physiologic indexes all returned to normal.The results pointed out:(1)HXHY could increase the blood SaO 2 and PaO 2.(2)It might affect the increase in the serum activity of RBC C 3b.(3)There was a significant decrease in plasma concentration of TXB 2.and 6 keto PGF 1a .(4)The plasmaTXB 2 and 6 keto PGF 1a ratio was increased because of the significant decrease of TXB 2 and 6 keto PGF 1a .Results showed that HXHY herbs had a good effect on ALI after abdominal surgical operations.