一些含氮杂环的脱氢松香酸甲酯衍生物的合成

Synthesis of Some Azo-heterocyclic Derivatives of Methyl Dehydroabietate

以歧化松香为原料,将其纯化得到脱氢松香酸,用硫酸二甲酯酯化后,通过12位溴代、7位氧化、脱异丙基硝化等步骤,得到了3个重要的中间体.该3个中间体分别经过亲核取代、还原关环反应后,得到了一些脱氢松香酸甲酯含氮杂环衍生物;产物结构经红外光谱、核磁共振谱、质谱和元素分析进行了表征.

Disproportionated rosin was purified to get dehydroabietic acid, which by esterification with （Me）2SO4 gave methyl dehydroabietate. Then methyl dehydroabietate was brominated at 12-position, oxidated at 7-position and deisopropyl-nitrated to give three important intermediates. By nucleophilic addition and reductive cyclization reaction of the three intermediates, respectively, some azo-heterocyclic derivatives containing a rosinyl skeleton were obtained. The compounds were characterized by IR, 1H NMR, 13C NMR, MS and elemental analyses.