蒙古族农牧民代谢综合征患病率及其危险因素的研究

Study on Prevalence of Metabolic Syndrome and Its Risk Factors of Mongolian People in Agricultural and Pastoral Areas

目的了解蒙古族农牧民代谢综合征(MS)患病率及其危险因素。方法选择内蒙古通辽市半农半牧地区的≥20岁常住蒙古族居民共2536人作为研究对象,采用现况研究方法,用统一设计的调查表,对研究对象进行面对面的问卷调查,采集血标本。测量身高、体质量、腰围、臀围及血压等指标;测定血糖、血脂及C反应蛋白(CRP)等生化指标。MS诊断标准采用中华医学会糖尿病学分会标准。结果MS粗患病率为9.3%,年龄标化患病率为8.1%,男性为7.6%,女性为8.6%。MS组分超重或肥胖、高血压、血脂紊乱及高血糖的患病率分别为20.2%、37.3%、35.8%及10.8%。调整了混杂因素后,高血压家族史、低密度脂蛋白胆固醇(LDL-C)、CRP、腰围、臀围及腰臀比6个因素与蒙古族农牧民MS差异仍均有统计学意义(均P<0.05)。结论当地蒙古族农牧民MS患病率较高,男性与女性MS患病率无差异。高血压家族史、LDL-C、CRP、腰围、臀围及腰臀比6个因素是蒙古族农牧民MS的独立危险因素。

Objective To investigate the prevalence of metabolic syndrome and its risk factors of Mongolian people in agricultural and pastoral areas. Methods A total of 2 536 Mongolian people aged 20 and elder from agricultural and pastoral areas in Tongliao City of Inner Mongolia were included in this study. A cross-sectional survey was conducted to collect data by personal interview with local residents using a standard questionnaire, as well as drawing fasting blood samples. Height, weight, waist circumference, hip circumference, blood pressure, fasting plasma glucose, blood fat and CRP were measured. Metabolic syndrome was diagnosed by means of using Chinese Diabetes Soeiety（CDS） definition. Results The crude prevalence of metabolic syndrome was 9.3%. The age-standardized prevalence of the metabolic syndrome was 8.1% （man 7.6%, woman 8.6%）. The prevalence of overweight or obesity, hypertension, dyslipidemia, and impaired glucose intolerance were 20.2%,37.3%,35.8% and 10.8% respectively. After controlling confounding factors, hypertension family history, LDL-C, CRP, waist circumference, hip circumference, and waist-hip rate Mongolian people in agricultural and pastoral areas were still risk factors of the metabolic syndrome of （P〈0.05）. Conclusion The prevalence of metabolic syndrome of local Mongolian people was high, and similar between males and females. After controlling confounding factors, hypertension family history, LDL-C, CRP, waist circumference, hip circumference, and waist-hip rate were independent risk factors of the metabolic syndrome of Mongolian people in agricultural and pastoral areas.