内镜下碘染色对Barrett食管的诊断价值

The Diagnostic Value of Barrett's Esophagus Using lodine Staining Under Endoscopy

目的探讨内镜下碘染色对Barrett食管的诊断价值。方法将内镜下考虑Barrett食管的病人82例随机分成两组,其中一组43例行碘染色后取活检,一组39例行常规内镜下活检。结果43例经内镜下碘染色后活检,病理诊断Barrett食管的为29例(66.44%),而常规内镜下活检诊断Barrett食管的为13例(33.33%),碘染色组的检出率明显高于非染色组,且经ROC曲线分析,内镜下碘染色组的ROC曲线下面积、灵敏度、特异度、阳性预测值和准确度明显高于常规内镜检查组。结论内镜下碘染色有助于提高Barrett食管的诊断率,在Barrett食管的诊断上具有重要的临床价值。

Objective To investigate the diagnostic value of Barrett＇ s esophagus using iodine staining under endoscopy. Methods 82 patients with suspected Barrett＇ s esophagus under endoscopy were observed, among them 43 patients were stained with iodine under endoscopy and then undergone biopsy, and 39 patients were undergone biopsy by routine endoscopy. Results 29 cases （66. 44% ）in the staining group were diagnosed Barrett＇ s esophagus by pathology examination, but only 13 cases（33.33% ） in the control were Barrett＇ s esophagus, so the diagnostic rate of the staining group was higher than the control. Under the analysis of ROC curve, the sensitivity, specificity, PPV and NPV of iodine staining group were all more higher than the routine group. Conclusion The Iodine staining under endoscopy can increase the diagnostic rate of Barrett＇ s esophagus, thus it is worthy of clinical application in diagnosis of Barrett＇ s esophagus.