小脑生物电治疗卒中后抑郁50例

Treatment of Post-Stroke Depression with Cerebellum Bioelectricity: A Report of 50 Cases

目的观察小脑生物电治疗卒中后抑郁(post-stroke depression,PSD)的疗效。方法将100例PSD患者采用随机双盲对照法分为治疗组和对照组,每组50例。2组患者均采用常规卒中治疗,均不使用抗抑郁药物。在此基础上,治疗组加用脑循环功能治疗仪进行小脑生物电治疗,共9周。2组患者治疗后分别于第1、3、5、7,9周进行汉密顿抑郁量表(HAMD)测评和HAMD减分率疗效评定,并记录不良反应。结果治疗组治疗后第9周HAMD评分、HAMD减分率与对照组比较差异均有统计学意义(P均<0.01)。治疗组1例因感冒、发热而中途退出治疗。结论小脑生物电治疗PSD患者疗效肯定,无严重不良反应发生,患者情绪好转,自信心强,并积极配合医生治疗脑卒中。

Objective To observe the effects of cerebellum bioelectricity on post-stroke depression（PSD）. Methods One hundred cases of PSD were divided into treatment group and control group using randomized double-blind controlled method,and each group had 50 cases. Both groups were treated for stroke generally, but not with anti-depression drugs. Being based on the above, the 50 cases in treatment group additionally were treated with cerebellum bioelectricity by cerebral circulation function treatment equipment for 9 weeks. Patients in the two groups after treatments were evaluated by HAMD scalogram and HAMD Reduced Rate on the 1,3,5,7,9 week resPectively. The side effects were also recorded. Results In the 9th week, both the differences of HAMD scalogram and HAMD Reduced Rate between treatment group and control group had statistical significance（all P〈0.01）. One case in treatment group dropped out for common cold and fever midway. Conclusion The effect of the treatment of PSD patients with cerebellum bioelectricity is positive and no severe side effects. The patients of PSD are better in mood and self-confidence and cooperate with doctors actively when treating their stroke.