双层羊膜植入联合小梁切除术治疗青光眼的疗效观察

Observing the Effect of Trabeculectomy with Double Amniotic Membrane Implantation on Glaucoma

目的：观察双层羊膜植入联合小梁切除术治疗原发性青光眼的临床疗效。方法：对35例40只眼原发性青光眼，其中22眼为闭角型青光眼、18眼为开角型青光眼，进行常规小梁切除术，并在巩膜瓣下植入双层羊膜。观察术后眼压、视野、视力等情况，进行了术前术后对比，并随访6-18个月，观察术后疗效。结果：术前术后眼压对比，术后眼压均有降低，视野及视力保持不变或改善，随访期间视力、眼压、视野维持良好。未出现不良反应。结论：双层羊膜植入联合小梁切除术可防止术后组织瘢痕形成，使滤过通道保持畅通，是安全、经济、有效的治疗青光眼的改良方法。

Objective： To evaluate the application of trabeculectomy with double amniotic membrane implantation on primary glaucoma. Methods： Double amniotic membrane was underlaid the scleral flap of trabeculectomy in 40 eyes of 35 patients with primary glaucoma, there were 22 eyes with angle closure glaucoma and 18 eyes with open angle glaucoma. Intraocular pressure （ IOP） , vision field and vision acuity were detected pre - or post - operation. The patients were followed up for 6-18 months. Results： lOP of post - operation was decreased compared with that of pre - operation. There was no significant difference or prograse in vision field and vision acuity between pre -or post -operation , without any special side effect. Conclusion： The results implied that trabeculectomy with double amniotic membrane implantation may play some roles in anti - fibrosis of filtering pathway after surgery and seems a simple, saffe and effective procedure of anti - glaucoma operations.