微波辐射碘化钾催化法合成甲基二磺酸钠

Synthesis of Sodium Methanedisulfonate Catalyzed by Potassium Iodide under Microwave Irradiation

在微波场中碘化钾催化亚硫酸钠与二氯甲烷发生亲核取代反应合成了甲基二磺酸钠。确定优化的反应条件为:亚硫酸钠、二氯甲烷、碘化钾和水的用量分别为3.7812 g(0.03 mol)、2.9 mL(0.045 mol)、0.0498 g(0.0003 mol)和30 mL,反应温度为80℃,微波辐射功率为500 W,微波辐射时间为60 min。此时甲基二磺酸钠产率可达78.32%。

Sodium methanedisulfonate was synthesized with sodium sulfite and methylene dichloride as starting materials through nucleophilic substitution reaction in the presence of catalyst of potassium iodide under microwave irradiation. The optimal synthetic conditions were determined as follows.dosages of sodium sulfite,methylene dichloride, potassium iodide and water were 3. 7812 g （0.03 mol） ,2.9 mL （0. 045 mol）, 0. 0498 g （0. 0003 mol） and 30 mL, respectively,the reaction temperature was 80℃ ,the microwave irradiation power was 500 W and the microwave irradiation time was 60 min. Under above conditions,the yield of sodium methanedisulfonate could reach 78. 32 %.