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早产儿支气管肺发育不良的病因及发病机制新进展 被引量：11

Progress in pathogenesis of bronchopulmonary dysplasia
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摘要 支气管肺发育不良是一种与早产相关的慢性肺部疾病，有较高的病死率和再入院率，目前尚缺乏有效的预防和治疗方法。它的病因尚不明确，目前认为是在遗传易患性的基础上，肺发育不成熟、肺损伤和损伤后的异常修复引起。肺部可见明显的炎症细胞及炎症因子的浸润，存在细胞的坏死和凋亡，同时在蛋白质水平及基因水平均有所改变。
作者 丁璐(综述) 吴本清(审校)
机构地区 暨南大学第二临床学院深圳市人民医院
出处 《国际儿科学杂志》 2008年第6期580-582,共3页 International Journal of Pediatrics
关键词 支气管肺发育不良 肺疾病 临床分析 治疗方法
分类号 R722.6 [医药卫生—儿科] R563 [医药卫生—呼吸系统]
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参考文献26

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同被引文献160

  • 1朱翠平,马祖祥.地塞米松对早产儿支气管肺发育不良预防作用的荟萃分析[J].广东医学,2006,27(3):415-418. 被引量：7
  • 2孙钦迎,张艳丽.早产儿支气管肺发育不良高危因素分析[J].山东医药,2006,46(18):27-28. 被引量：4
  • 3常立文.新生儿支气管肺发育不良诊治进展[J].临床儿科杂志,2007,25(3):161-165. 被引量：46
  • 4常立文.新生儿支气管肺发育不良的诊治[J].中国实用儿科杂志,2007,22(4):241-243. 被引量：16
  • 5Doyle LW,Ehrenkranz RA,Halliday HL.Dexamethasone treatment after the first week of life for bronchopulmonary dysplasia in preterm infants:a systematic review.Neonatology,2010,98 (4):289-296.
  • 6Northway WH Jr,Rosan RC,Porter DY.Pulmonary disease following respirator therapy of hyaline-membrane disease.Bronchopulmonary dysplasia.N Engl J Med,1967,276 (7):357-368.
  • 7Kinsella JP,Greenough A,Abman SH.Bronchopulmonary dysplasia.Lancet,2006,367(9520):1421-1431.
  • 8Monte LF,Silva Filho LV,Miyoshi MH,et al.Bronchopulmonary dysplasia.J Pediatr,2005,81(2):99-110.
  • 9ter Horst SA,Walther FJ,Poorthuis BJ,et al.Inhaled nitric oxide attenuates pulmonary inflammation and fibrin deposition and prolongs survival in neonatal hyperoxic lung injury.Am J Physiol Lung Cell Mol Physiol,2007,293(1):L35-44.
  • 10Mercier JC,Hummler H,Durrmeyer X,et al.Inhaled nitric oxide for prevention of bronchopulmonary dysplasia in premature babies (EUNO):a randomised controlled trial.Lancet,2010,376(9738):346-354.

引证文献11

二级引证文献52

国际儿科学杂志
2008年 第6期

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