摘要
目的研究比较国产缬草属4种药用植物的镇静催眠活性。方法通过观察其乙醇提取物对小鼠自主活动及戊巴比妥钠诱导小鼠睡眠时间的影响来评价其镇静催眠活性。结果中国缬草、宽叶缬草、蜘蛛香、黑水缬草均具有镇静催眠活性,以宽叶缬草和蜘蛛香活性较强。结论宽叶缬草及蜘蛛香药用植物等在镇静催眠方面具有开发利用潜力。
Objective To investigate the sedative and hypnotic actions of four species of Valeriana L. Methods The hypnotic and sedative actions were observed by the spontaneous activity and pentobarbital sodium induced sleeping time in mice. Results They all had sedative and hypnotic actions, and V. officinalis var. latifolia and V. jatamansi showed higher activities. Conclusion - They have value in development of sedative and hypnotics.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2008年第11期2710-2711,共2页
Lishizhen Medicine and Materia Medica Research
基金
国家自然科学基金(No.30270152)
上海-联合利华研究与发展基金(No.06SU07005)
关键词
缬草属
药用植物
镇静
催眠
Valeriana L.
Medicinal plant
Hypnotic
Sedative
