无创通气治疗重症哮喘82例疗效观察

Observation on the effect of noninvasive ventilation in treating severe asthma

目的:探讨无创通气在重症哮喘中的疗效。方法:82例重症哮喘患者随机分为三组:BiPAP治疗组、有创通气治疗组、常规治疗组。比较三组实施治疗前、治疗3d后患者临床症状、体征变化及动脉血气指标(pH、PaCO2、PaO2、SaO2)变化。结果:B iPAP组与常规组比较差异有统计学意义,与有创通气组比较差异无统计学意义。结论:在常规治疗的基础加用无创通气治疗,可有效改善患者的临床症状,改善通气,提高重症哮喘的治疗效果。

Objective To study the effect of noninvasive ventilation in treating severe asthma. Method Eighty - two eases with severe asthma were divided into three groups ： BiPAP group, invasive ventilation group and routine treatment group. The changes of clinieal symptoms and arterial blood gas （pH, PaCO2, PaO2 and SaO2 ）before and 3 days after treatment were compared. Results There was obvious difference between routine treatment group and BiPAP group, and the difference between invasive ventilation group and BiPAP group is not striking. Conclusion Using noninvasive Ventilation based on routine treatment can improved the clinical manifestation and raise the curative effeet of severe asthma.