川芎嗪注射液联合激素、抗生素治疗放射性肺炎临床观察

Ligustrazine Injection together with Hormone and Antibiotic Treat Radioactive Pneumonia

[目的]观察川芎嗪注射液联合激素、抗生素治疗放射性肺炎的疗效。[方法]胸部肿瘤接受放射治疗中或放射治疗后诊断为放射性肺炎77例患者随机分为两组,对照组38例,使用糖皮质激素、抗生素治疗;治疗组39例,加用川芎嗪注射液治疗。比较两组患者的临床症状、X线表现和肺功能改变。[结果]39例治疗组病人,治愈21例(53.85%),好转15例(38.46%),有效率92.31%;对照组38例,治愈13例(34.21%),好转14例(35.90%),有效率71.05%。两组疗效差异有统计学意义(P<0.05)。肺功能以最大通气量(MVV)和第一秒用力呼出量(FEV1.0)比率来作为评价标准。治疗组肺功能改善明显优于对照组。[结论]川芎嗪注射液联合激素、抗生素治疗放射性肺炎有良好的临床疗效。

[Objective]To Observe the cure effect of ligustrazine injection combined with hormone and antibiotic on radioactive pneumonia. [Method]77 patients were randomly divided into 2 groups,the control group 38 cases used glucocorticoid and antibiotic;the treatment one 39 added litustrazine injection. Compare their clinical symptoms, X-ray and lung function changes. [Result] In the treatment group,21 were cured（53.85%）,15 better（38.46%）,the effective rate 92.31% ; 13（34.21%）,14（35.90%） and 71. 05 % respectively for the control group. There＇s statistical meaning for the difference between both groups（P〈0.05）. Take the ratio of MVV and FEV1.0 as appraisal standard;the improvement of lung function was obviously better than control one. [Conclusion]Ligustrazine injection combined with hormone and antibiotic has good clinical therapeutic effect on radioactive pneumonia.